Novel Inhibitors of Acetyl- and Butyrylcholinesterase Derived from Benzohydrazides: Synthesis, Evaluation and Docking Study

• Main Authors: Neto-Honorius Houngbedji (Author), Šárka Štěpánková (Author), Václav Pflégr (Author), Katarína Svrčková (Author), Markéta Švarcová (Author), Jarmila Vinšová (Author), Martin Krátký (Author)
• Format: Knjiga
• Izdano: MDPI AG, 2023-01-01T00:00:00Z.
• Teme: article
• Online dostop: Connect to this object online.

On the basis of previous reports, novel 2-benzoylhydrazine-1-carboxamides were designed as potential inhibitors of acetylcholinesterase (AChE) and butyrylcholinesterase (BChE). Inhibitors of these enzymes have many clinical applications. 2-(Substituted benzoyl)hydrazine-1-carboxamides decorated with...