Population pharmacokinetic analysis for dose regimen optimization of vancomycin in Southern Chinese children

• Main Authors: Xianhuan Shen (Author), Xuejuan Li (Author), Jieluan Lu (Author), Jiahao Zhu (Author), Yaodong He (Author), Zhou Zhang (Author), Zebin Chen (Author), Jianping Zhang (Author), Xiaomei Fan (Author), Wenzhou Li (Author)
• Format: Book
• Published: Wiley, 2024-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Changes in physiological factors may result in large pharmacokinetic variability of vancomycin in pediatric patients, thereby leading to either supratherapeutic or subtherapeutic exposure and potentially affecting clinical outcomes. This study set out to characterize the disposition of vanc...