Population pharmacokinetic analysis for dose regimen optimization of vancomycin in Southern Chinese children

• Autores principales: Xianhuan Shen (Autor), Xuejuan Li (Autor), Jieluan Lu (Autor), Jiahao Zhu (Autor), Yaodong He (Autor), Zhou Zhang (Autor), Zebin Chen (Autor), Jianping Zhang (Autor), Xiaomei Fan (Autor), Wenzhou Li (Autor)
• Formato: Libro
• Publicado: Wiley, 2024-07-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Abstract Changes in physiological factors may result in large pharmacokinetic variability of vancomycin in pediatric patients, thereby leading to either supratherapeutic or subtherapeutic exposure and potentially affecting clinical outcomes. This study set out to characterize the disposition of vanc...