Influence of Pathogenic and Metabolic Genes on the Pharmacogenetics of Mood Disorders in Alzheimer's Disease

• Main Authors: Ramón Cacabelos (Author), Juan C. Carril (Author), Lola Corzo (Author), Lucía Fernández-Novoa (Author), Rocío Pego (Author), Natalia Cacabelos (Author), Pablo Cacabelos (Author), Margarita Alcaraz (Author), Iván Tellado (Author), Vinogran Naidoo (Author)
• Format: Book
• Published: MDPI AG, 2021-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Mood disorders represent a risk factor for dementia and are present in over 60% of cases with Alzheimer's disease (AD). More than 80% variability in drug pharmacokinetics and pharmacodynamics is associated with pharmacogenetics. Methods: Anxiety and depression symptoms were assessed...