Participation of quetiapine in oxidative stress and inflammation status in the treatment of drug overdose

• Main Authors: Karina Sommerfeld-Klatta (Author), Magdalena Łukasik-Głębocka (Author), Ewelina Krawczak (Author), Anna Stodolska (Author), Barbara Zielińska-Psuja (Author)
• Format: Book
• Published: Polskie Towarzystwo Farmaceutyczne, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Quetiapine (QT) belongs to the second generation of antipsychotics. It is mostly used to treat depression, bipolar disorder, and schizophrenia. During biotransformation via myeloperoxidase (MPO) QT is oxidized to quinoneimine and a reactive radical, which may contribute to the development of oxidati...