Gut Microbiome Alters the Activity of Liver Cytochromes P450 in Mice With Sex-Dependent Differences

• Main Authors: Lenka Jourová (Author), Marketa Vavreckova (Author), Nina Zemanova (Author), Pavel Anzenbacher (Author), Katerina Langova (Author), Petra Hermanova (Author), Tomas Hudcovic (Author), Eva Anzenbacherova (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sexual differences and the composition/function of the gut microbiome are not considered the most important players in the drug metabolism field; however, from the recent data it is obvious that they may significantly affect the response of the patient to therapy. Here, we evaluated the effect of mi...