Effect of Administration Route on the Pharmacokinetics of Cobalamin in Elderly Patients: A Randomized Controlled Trial

• Main Authors: Monique P.H. Tillemans, PharmD (Author), Eline M.V.J. Donders, MD (Author), Sjoerd L. Verweij, PharmD (Author), Ruud T.M. Van der Hoeven, PharmD (Author), Kees J. Kalisvaart, MD, PhD (Author)
• Format: Book
• Published: Elsevier, 2014-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The gold standard for cobalamin deficiency treatment is administration of cobalamin by intramuscular injection. The injection is painful and inconvenient, particularly for elderly persons. Cobalamin might also be administered intranasally. Previous studies do not provide insight into the...