A physiologically based pharmacokinetic model of clopidogrel in populations of European and Japanese ancestry: An evaluation of CYP2C19 activity

ABSTRACT Treatment response to clopidogrel is associated with CYP2C19 activity through the formation of the active H4 metabolite. The aims of this study were to develop a physiologically based pharmacokinetic (PBPK) model of clopidogrel and its metabolites for populations of European ancestry, to pr...

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Main Authors: Janna K. Duong (Author), Romina A. Nand (Author), Aarti Patel (Author), Oscar Della Pasqua (Author), Annette S. Gross (Author)
Format: Book
Published: Wiley, 2022-04-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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