MMP1-1607 polymorphism increases the risk for periapical lesion development through the upregulation MMP-1 expression in association with pro-inflammatory milieu elements

• Main Authors: Ana Paula Favaro TROMBONE (Author), Franco CAVALLA (Author), Elcia Maria Varize SILVEIRA (Author), Camile Bermejo ANDREO (Author), Carolina Favaro FRANCISCONI (Author), Angélica Cristina FONSECA (Author), Ariadne LETRA (Author), Renato Menezes SILVA (Author), Gustavo Pompermaier GARLET (Author)
• Format: Book
• Published: University of São Paulo.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT Increased matrix metalloproteinases (MMPs) activity is a hallmark of periapical granulomas. However, the factors underlying the MMPs expression modulation in healthy and diseased periapical tissues remains to be determined. Objective In this study, we evaluated the association between the M...