Virtual Screening of Potential RoxS Inhibitors and Evaluation of Their Antimicrobial Activity in Combination with Antibiotics against Clinically Resistant Bacteria

• Main Authors: Ya-Yan Huang (Author), Jia-Hao Li (Author), Ting-Ting Liang (Author), Ze-An Zhao (Author), Jun Xu (Author), Wen-Ying Chen (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<i>Pseudomonas aeruginosa</i> with difficult-to-treat resistance has been designated as an urgent or serious threat by the CDC in the United States; therefore, novel antibacterial drugs and combination strategies are urgently needed. The sensor kinase RoxS is necessary for the aerobic gr...