PPAR Gamma Agonist Leriglitazone Recovers Alterations Due to Pank2-Deficiency in hiPS-Derived Astrocytes

• Główni autorzy: Paolo Santambrogio (Autor), Anna Cozzi (Autor), Ivano Di Meo (Autor), Chiara Cavestro (Autor), Cristina Vergara (Autor), Laura Rodríguez-Pascau (Autor), Marc Martinell (Autor), Pilar Pizcueta (Autor), Valeria Tiranti (Autor), Sonia Levi (Autor)
• Format: Książka
• Wydane: MDPI AG, 2023-01-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

The novel brain-penetrant peroxisome proliferator-activated receptor gamma agonist leriglitazone, previously validated for other rare neurodegenerative diseases, is a small molecule that acts as a regulator of mitochondrial function and exerts neuroprotective, anti-oxidative and anti-inflammatory ef...