IGF-1-Overexpressing Mesenchymal Stem/Stromal Cells Promote Immunomodulatory and Proregenerative Effects in Chronic Experimental Chagas Disease

• Main Authors: Daniela N. Silva (Author), Bruno S. F. Souza (Author), Carine M. Azevedo (Author), Juliana F. Vasconcelos (Author), Paloma G. de Jesus (Author), Malena S. Feitoza (Author), Cassio S. Meira (Author), Gisele B. Carvalho (Author), Bruno Raphael Cavalcante (Author), Ricardo Ribeiro- (Author), Milena B. P. Soares (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Mesenchymal stem/stromal cells (MSCs) have been investigated for the treatment of diseases that affect the cardiovascular system, including Chagas disease. MSCs are able to promote their beneficial actions through the secretion of proregenerative and immunomodulatory factors, including insulin-like...