Glibenclamide Alleviates LPS-Induced Acute Lung Injury through NLRP3 Inflammasome Signaling Pathway

• Main Authors: Jie Yang (Author), Jiawen Yang (Author), Xiaofang Huang (Author), Huiqing Xiu (Author), Songjie Bai (Author), Jiahui Li (Author), Zhijian Cai (Author), Zhanghui Chen (Author), Shufang Zhang (Author), Gensheng Zhang (Author)
• Format: Book
• Published: Hindawi Limited, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Glibenclamide displays an anti-inflammatory response in various pulmonary diseases, but its exact role in lipopolysaccharide- (LPS-) induced acute lung injury (ALI) or acute respiratory distress syndrome (ARDS) remains unknown. Herein, we aimed to explore the effect of glibenclamide in vivo and in v...