Protective Effects of Oridonin on Acute Liver Injury via Impeding Posttranslational Modifications of Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) in the Toll-Like Receptor 4 (TLR4) Signaling Pathway

• Päätekijät: Min Shi (Tekijä), Yilin Deng (Tekijä), Heguo Yu (Tekijä), Ling Xu (Tekijä), Cuicui Shi (Tekijä), Jiong Chen (Tekijä), Guangming Li (Tekijä), Yiqi Du (Tekijä), Yu-gang Wang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Hindawi Limited, 2019-01-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Objective. Recent researches have demonstrated that inflammation-related diseases are effectively regulated by posttranslational modifications (PTMs) including phosphorylation and acetylation. Our previous study found a new acetyltransferase inhibitor, oridonin, which had a protective effect on acut...