Protective Effects of Oridonin on Acute Liver Injury via Impeding Posttranslational Modifications of Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) in the Toll-Like Receptor 4 (TLR4) Signaling Pathway

• मुख्य लेखकों: Min Shi (लेखक), Yilin Deng (लेखक), Heguo Yu (लेखक), Ling Xu (लेखक), Cuicui Shi (लेखक), Jiong Chen (लेखक), Guangming Li (लेखक), Yiqi Du (लेखक), Yu-gang Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Hindawi Limited, 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Objective. Recent researches have demonstrated that inflammation-related diseases are effectively regulated by posttranslational modifications (PTMs) including phosphorylation and acetylation. Our previous study found a new acetyltransferase inhibitor, oridonin, which had a protective effect on acut...