RNAi effector diversity in nematodes.

• Main Authors: Johnathan J Dalzell (Author), Paul McVeigh (Author), Neil D Warnock (Author), Makedonka Mitreva (Author), David McK Bird (Author), Pierre Abad (Author), Colin C Fleming (Author), Tim A Day (Author), Angela Mousley (Author), Nikki J Marks (Author), Aaron G Maule (Author)
• 格式: 图书
• 出版: Public Library of Science (PLoS), 2011-06-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

While RNA interference (RNAi) has been deployed to facilitate gene function studies in diverse helminths, parasitic nematodes appear variably susceptible. To test if this is due to inter-species differences in RNAi effector complements, we performed a primary sequence similarity survey for orthologs...