The Analysis of In Vivo Aging in Human Bone Marrow Mesenchymal Stromal Cells Using Colony-Forming Unit-Fibroblast Assay and the CD45lowCD271+ Phenotype

The Analysis of In Vivo Aging in Human Bone Marrow Mesenchymal Stromal Cells Using Colony-Forming Unit-Fibroblast Assay and the CD45lowCD271+ Phenotype

Uncultured mesenchymal stromal cells (MSCs) are increasingly used in therapies; however, the effects of donor age on their biological characteristics and gene expression remain unclear. The aim of this study was to investigate age-related changes in bone marrow (BM) MSCs following minimal or no cult...

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Main Authors: Payal Ganguly (Author), Jehan J. El-Jawhari (Author), Agata N. Burska (Author), Frederique Ponchel (Author), Peter V. Giannoudis (Author), Elena A. Jones (Author)
Format: Book
Published: Hindawi Limited, 2019-01-01T00:00:00Z.
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