Synthesis of salcaprozate sodium and its significance in enhancing pancreatic kininogenase absorption performance

• Main Authors: Zhong Lv (Author), Qian‐Dong Luo (Author), Zhang‐Yong Tang (Author), Xiao‐Hu Lv (Author), Tao Wu (Author), Ling‐Kai Huang (Author), Can Tang (Author)
• Format: Book
• Published: Wiley, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We conducted pharmacokinetic research wherein salcaprozate sodium (SNAC) was utilized as a penetration enhancer by incorporating it into pancreatic kininogenase (PK) to improve the bioavailability of pancreatic kininogenase enteric‐coated tablets. We conducted in vitro studies on PK using t...