Effect of the Natural Product Triptolide on Pancreatic Cancer: A Systematic Review of Preclinical Studies

• Prif Awduron: Chi Zhang (Awdur), Xiao-Juan He (Awdur), Li Li (Awdur), Cheng Lu (Awdur), Ai-Ping Lu (Awdur)
• Fformat: Llyfr
• Cyhoeddwyd: Frontiers Media S.A., 2017-08-01T00:00:00Z.
• Pynciau: article
• Mynediad Ar-lein: Connect to this object online.

Objective: Triptolide (TL), a natural product isolated from Tripterygium wilfordii Hook F (TwHF), shows potent anticancer effects in vitro and in vivo. We aimed to summary the biochemical mechanisms through which TL has been shown to induce apoptosis, autophagy and inhibit angiogenesis in pancreatic...