Survivin Improves Reprogramming Efficiency of Human Neural Progenitors by Single Molecule OCT4

• Main Authors: Shixin Zhou (Author), Yinan Liu (Author), Ruopeng Feng (Author), Caiyun Wang (Author), Sibo Jiang (Author), Xiaoyan Zhang (Author), Feng Lan (Author), Yang Li (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Induced pluripotent stem (iPS) cells have been generated from human somatic cells by ectopic expression of four Yamanaka factors. Here, we report that Survivin, an apoptosis inhibitor, can enhance iPS cells generation from human neural progenitor cells (NPCs) together with one factor OCT4 (1F-OCT4-S...