Combined Activity of the Redox-Modulating Compound Setanaxib (GKT137831) with Cytotoxic Agents in the Killing of Acute Myeloid Leukemia Cells

Combined Activity of the Redox-Modulating Compound Setanaxib (GKT137831) with Cytotoxic Agents in the Killing of Acute Myeloid Leukemia Cells

Acute myeloid leukemia (AML) cells harbor elevated levels of reactive oxygen species (ROS), which promote cell proliferation and cause oxidative stress. Therefore, the inhibition of ROS formation or elevation beyond a toxic level have been considered as therapeutic strategies. ROS elevation has rece...

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Main Authors: Muhammed Burak Demircan (Author), Peter C. Mgbecheta (Author), Anne Kresinsky (Author), Tina M. Schnoeder (Author), Katrin Schröder (Author), Florian H. Heidel (Author), Frank D. Böhmer (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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