An Experimental Model of Prolonged Esophagitis With Sphincter Failure in the Rat and the Therapeutic Potential of Gastric Pentadecapeptide BPC 157

• Main Authors: Igor Petrovic (Author), Ivan Dobric (Author), Petar Drvis (Author), Drazen Shejbal (Author), Luka Brcic (Author), Alenka Boban Blagaic (Author), Lovorka Batelja (Author), Neven Kokic (Author), Ante Tonkic (Author), Stjepan Mise (Author), Tomislav Baotic (Author), Mario Staresinic (Author), Bozo Radic (Author), Ana Jakir (Author), Tihomir Vuksic (Author), Tomislav Anic (Author), Sven Seiwerth (Author), Predrag Sikiric (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We report a simple novel rat model that combines prolonged esophagitis and parallel sphincters failure. The anti-ulcer gastric pentadecapeptide BPC 157, which was found to be stable in gastric juice, and is being evaluated in inflammatory bowel disease trials, is an antiesophagitis therapy that reco...