EM23, a natural sesquiterpene lactone from Elephantopus mollis H.B.K., induces apoptosis in human myeloid leukemia cells through thioredoxin- and reactive oxygen species-mediated signaling pathways

• Egile Nagusiak: Hongyu eLi (Egilea), Manmei eLi (Egilea), Guocai eWang (Egilea), Fangyuan eShao (Egilea), Wenbo eChen (Egilea), Chao eXia (Egilea), Sheng eWang (Egilea), Yaolan eLi (Egilea), Guangxiong eZhou (Egilea), Zhong eLiu (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2016-03-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Elephantopus mollis H.B.K. (EM) is a traditional herbal medicine with multiple pharmacological activities. However, the efficacy of EM in treating human leukemia is currently unknown. In the current study, we report that EM23, a natural sesquiterpene lactone isolated from EM, inhibits the proliferat...