Improving the dissolution properties of spironolactone using liquisolid technique

• Main Authors: Jafar Akbari (Author), Majid Saeedi (Author), Katayoun Morteza-Semnani (Author), Zaynab Sadeghi Ghadi (Author), Seyed Saeed Hosseini (Author)
• Format: Book
• Published: Mazandaran University of Medical Sciences, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In this study the effect of liquisolid technique on the dissolution profile of spironolactone was evaluated. Different formulations of spironolactone liquisolid compacts were prepared using various amounts of non-volatile vehicles (Poly ethylene glycol 400 and glycerin). The ratio of microcrystallin...