Comparative proteomic analysis of normal and tumor stromal cells by tissue on chip based mass spectrometry (toc-MS)

• Main Authors: Friedrich Karlheinz (Author), Junker Kerstin (Author), Clement Joachim H (Author), Berndt Alexander (Author), Melle Christian (Author), Ernst Günther (Author), Escher Niko (Author), Guntinas-Lichius Orlando (Author), von Eggeling Ferdinand (Author)
• Format: Book
• Published: BMC, 2010-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>In carcinoma tissues, genetic and metabolic changes not only occur at the tumor cell level, but also in the surrounding stroma. This carcinoma-reactive stromal tissue is heterogeneous and consists e.g. of non-epithelial cells such as fibroblasts or fibrocytes, in...