Cardiac Niche Influences the Direct Reprogramming of Canine Fibroblasts into Cardiomyocyte-Like Cells

• Main Authors: Giacomo Palazzolo (Author), Mattia Quattrocelli (Author), Jaan Toelen (Author), Roberto Dominici (Author), Luigi Anastasia (Author), Guido Tettamenti (Author), Inès Barthelemy (Author), Stephane Blot (Author), Rik Gijsbers (Author), Marco Cassano (Author), Maurilio Sampaolesi (Author)
• Format: Book
• Published: Hindawi Limited, 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The Duchenne and Becker muscular dystrophies are caused by mutation of dystrophin gene and primarily affect skeletal and cardiac muscles. Cardiac involvement in dystrophic GRMD dogs has been demonstrated by electrocardiographic studies with the onset of a progressive cardiomyopathy similar to the ca...