Predicting model‐informed precision dosing: A test‐case in tacrolimus dose adaptation for kidney transplant recipients

• Main Authors: Ruben Faelens (Author), Nicolas Luyckx (Author), Dirk Kuypers (Author), Thomas Bouillon (Author), Pieter Annaert (Author)
• 格式: 图书
• 出版: Wiley, 2022-03-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Before investing resources into the development of a precision dosing (model‐informed precision dosing [MIPD]) tool for tacrolimus, the performance of the tool was evaluated in silico. A retrospective dataset of 315 de novo kidney transplant recipients was first used to identify a one‐compa...