How to improve the early diagnosis of Trypanosoma cruzi infection: relationship between validated conventional diagnosis and quantitative DNA amplification in congenitally infected children.

• Main Authors: Jacqueline Bua (Author), Bibiana J Volta (Author), Alina E Perrone (Author), Karenina Scollo (Author), Elsa B Velázquez (Author), Andres M Ruiz (Author), Ana M De Rissio (Author), Rita L Cardoni (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: According to the Chagas congenital transmission guides, the diagnosis of infants, born to Trypanosoma cruzi infected mothers, relies on the detection of parasites by INP micromethod, and/or the persistence of T. cruzi specific antibody titers at 10-12 months of age. METHODOLOGY AND PRINC...