Drug Content Uniformity: Quantifying Loratadine in Tablets Using a Created Raman Excipient Spectrum

• Main Authors: Amelia Farquharson (Author), Zachery Gladding (Author), Gary Ritchie (Author), Chetan Shende (Author), Joseph Cosgrove (Author), Wayne Smith (Author), Carl Brouillette (Author), Stuart Farquharson (Author)
• Format: Book
• Published: MDPI AG, 2021-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Raman spectroscopy has proven valuable for determining the composition of manufactured drug products, as well as identifying counterfeit drugs. Here we present a simple method to determine the active pharmaceutical ingredient (API) mass percent in a sample that does not require knowledge of the iden...