A practical assessment protocol for clinically relevant P-glycoprotein-mediated drug-drug interactions

• Main Authors: Leonie Bogaard (Author), Kayan Tsoi (Author), Bas van de Steeg (Author), Esther F. A. Brandon (Author), Lisanne Geers (Author), Margreet van Herwaarden (Author), Frank Jansman (Author), Dominique Maas (Author), Margje Monster-Simons (Author), David S. Y. Ong (Author), Sander D. Borgsteede (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundDrug-drug interactions (DDIs) may influence the effectiveness and safety of medication treatment, which may require additional monitoring, dose adjustment or avoidance of certain drugs. DDIs involving P-glycoprotein (P-gp) affect many drugs, but current official product information is ofte...