Leptin and insulin engage specific PI3K subunits in hypothalamic SF1 neurons

• Hauptverfasser: Jong-Woo Sohn (Verfasst von), Youjin Oh (Verfasst von), Ki Woo Kim (Verfasst von), Syann Lee (Verfasst von), Kevin W. Williams (Verfasst von), Joel K. Elmquist (Verfasst von)
• Format: Buch
• Veröffentlicht: Elsevier, 2016-08-01T00:00:00Z.
• Schlagworte: article
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Objective: The ventromedial hypothalamic nucleus (VMH) regulates energy balance and glucose homeostasis. Leptin and insulin exert metabolic effects via their cognate receptors expressed by the steroidogenic factor 1 (SF1) neurons within the VMH. However, detailed cellular mechanisms involved in the...