Two Distinct Effects of cGMP on Cytosolic Ca2+ Concentration of Rat Pancreatic β-Cells

• Главные авторы: Tomohisa Ishikawa (Автор), Yukiko Kaneko (Автор), Fumi Sugino (Автор), Koichi Nakayama (Автор)
• Формат: ‌
• Опубликовано: Elsevier, 2003-01-01T00:00:00Z.
• Предметы: article
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The present study investigated the effects of cGMP on cytosolic Ca2+ concentration ([Ca2+]c) of isolated rat pancreatic β-cells. In the presence of 7.0 mM glucose, NOC 7, a nitric oxide (NO) donor, caused an increase in [Ca2+]c of the β-cells, which was abolished by the soluble guanylate cyclase inh...