Leonurine promotes the maturation of healthy donors and multiple myeloma patients derived-dendritic cells via the regulation on arachidonic acid metabolism

• Egile Nagusiak: Cheng Chen (Egilea), Lin He (Egilea), Xi Wang (Egilea), Rong Xiao (Egilea), Shu Chen (Egilea), Zichen Ye (Egilea), Xuemei Wang (Egilea), Yu Wang (Egilea), Yizhun Zhu (Egilea), Jingying Dai (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2023-01-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Objective: Leonurine is a bioactive alkaloid compound extracted from Leonurus japonicus Houtt, which potentially has immunomodulatory effects. The immunomodulatory effect and mechanism of leonurine on monocyte derived dendritic cells (moDCs) from healthy donors (HDs) and multiple myeloma (MM) patien...