Hepatocyte-targeting and tumor microenvironment-responsive liposomes for enhanced anti-hepatocarcinoma efficacy

• Hauptverfasser: Dongliang Cheng (Verfasst von), Zhiwei Wen (Verfasst von), Hui Chen (Verfasst von), Shiyuan Lin (Verfasst von), Wei Zhang (Verfasst von), Xin Tang (Verfasst von), Wei Wu (Verfasst von)
• Format: Buch
• Veröffentlicht: Taylor & Francis Group, 2022-12-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

To increase the antitumor drug concentration in the liver tumor site and improve the therapeutic effects, a functionalized liposome (PPP-LIP) with tumor targetability and enhanced internalization after matrix metalloproteinase-2 (MMP2)-triggered cell-penetrating peptide (TATp) exposure was modified...