Pharmacokinetic Comparison between Methotrexate-Loaded Nanoparticles and Nanoemulsions as Hard- and Soft-Type Nanoformulations: A Population Pharmacokinetic Modeling Approach

• Main Authors: Seung-Hyun Jeong (Author), Ji-Hun Jang (Author), Yong-Bok Lee (Author)
• 格式: 圖書
• 出版: MDPI AG, 2021-07-01T00:00:00Z.
• 主題: article
• 在線閱讀: Connect to this object online.

The purpose of this study was to identify and explore the differences in pharmacokinetics between different nanoformulations. This was done by comparing the pharmacokinetics of methotrexate-loaded nanoparticles [poly(lactic-co-glycolic acid); size of 163.70 ± 10.25 nm] and nanoemulsions (olive oil a...