Genome-wide association study for circulating FGF21 in patients with alcohol use disorder: Molecular links between the SNHG16 locus and catecholamine metabolism

• Main Authors: Ming-Fen Ho (Author), Cheng Zhang (Author), Irene Moon (Author), Lixuan Wei (Author), Brandon Coombes (Author), Joanna Biernacka (Author), Michelle Skime (Author), Doo-Sup Choi (Author), Mark Frye (Author), Kristen Schmidt (Author), Kate Gliske (Author), Jacqueline Braughton (Author), Quyen Ngo (Author), Cedric Skillon (Author), Marvin Seppala (Author), Tyler Oesterle (Author), Victor Karpyak (Author), Hu Li (Author), Richard Weinshilboum (Author)
• Format: Book
• Published: Elsevier, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Alcohol consumption can increase circulating levels of fibroblast growth factor 21 (FGF21). The effects of FGF21 in the central nervous system are associated with the regulation of catecholamines, neurotransmitters that play a crucial role in reward pathways. This study aims to identify g...