A Population Pharmacokinetic and Pharmacodynamic Model of CKD-519

CKD-519 is a selective and potent cholesteryl ester transfer protein (CETP) inhibitor that is being developed for dyslipidemia. Even though CKD-519 has shown potent CETP inhibition, the exposure of CKD-519 was highly varied, depending on food and dose. For highly variable exposure drugs, it is cruci...

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Main Authors: Choon Ok Kim (Author), Sangil Jeon (Author), Seunghoon Han (Author), Min Soo Park (Author), Dong-Seok Yim (Author)
Format: Book
Published: MDPI AG, 2020-06-01T00:00:00Z.
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