Designing fisetin nanocrystals for enhanced in cellulo anti-angiogenic and anticancer efficacy

• Main Authors: Panpan Ma (Author), Johanne Seguin (Author), Nhu Ky Ly (Author), Luis Castillo Henríquez (Author), Eva Plansart (Author), Karim Hammad (Author), Rabah Gahoual (Author), Hélène Dhôtel (Author), Charlotte Izabelle (Author), Bruno Saubamea (Author), Cyrille Richard (Author), Virginie Escriou (Author), Nathalie Mignet (Author), Yohann Corvis (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We report the formulation, characterization, colloidal stability, and in vitro efficiency of Fisetin nanocrystals stabilized by poloxamer P407. Such nanocrystals present a nanometer scale (148.6 ± 1.1 nm) and a high homogeneity (polydispersity index of 0.17 ± 0.01), with a production yield of 97.0 ±...