Amorphous Nanosuspensions Aggregated from Paclitaxel-Hemoglobulin Complexes with Enhanced Cytotoxicity

• Main Authors: Chao Qin (Author), Xiaofei Xin (Author), Xue Pei (Author), Lifang Yin (Author), Wei He (Author)
• Formato: Livro
• Publicado em: MDPI AG, 2018-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Amorphous nanosuspensions (ANSs) enable rapid release and improved delivery of a poorly water-soluble drug; however, their preparation is challenging. Here, using hemoglobin (Hb) as a carrier, ANSs aggregated from paclitaxel (PTX)–Hb complexes were prepared to improve delivery of the hydro...