Microbiome-Metabolomics Analysis Reveals the Protection Mechanism of α-Ketoacid on Adenine-Induced Chronic Kidney Disease in Rats

• Main Authors: Yenan Mo (Author), Huang Sun (Author), Lei Zhang (Author), Wenjia Geng (Author), Lixin Wang (Author), Chuan Zou (Author), Yuchi Wu (Author), Chunlan Ji (Author), Xusheng Liu (Author), Zhaoyu Lu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objectives: As nitrogen-free precursors of corresponding essential amino, α-ketoacid have been widely prescribed to end-stage renal disease patients together with a low protein diet However, the impact of α-ketoacid on intestinal microbiota in chronic kidney disease (CKD) individuals is unknown. The...