Intracellular Fate of the Photosensitizer Chlorin e4 with Different Carriers and Induced Metabolic Changes Studied by ¹H NMR Spectroscopy

• मुख्य लेखकों: Martina Vermathen (लेखक), Tobias Kämpfer (लेखक), Jean-Marc Nuoffer (लेखक), Peter Vermathen (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2023-09-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Porphyrinic photosensitizers (PSs) and their nano-sized polymer-based carrier systems are required to exhibit low dark toxicity, avoid side effects, and ensure high in vivo tolerability. Yet, little is known about the intracellular fate of PSs during the dark incubation period and how it is affected...