Effect of concomitant administration of nifedipine and tacrolimus on the development of gingival overgrowth in rats

• Main Authors: Sheng-Yi Chen (Author), Cheng-Yang Chiang (Author), Yu-Wen Yeh (Author), Hsiao-Pei Tu (Author), Hsien-Chung Chiu (Author), Shin Nieh (Author), Earl Fu (Author)
• Format: Book
• Published: Elsevier, 2015-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background/purpose: It is still controversial whether tacrolimus can induce gingival overgrowth. Calcium channel blockers of nifedipine are commonly used for lessening the side effect of high blood pressure induced by tacrolimus; however, nifedipine can also induce gingival overgrowth. This study wa...