Luteolin sensitizes the antitumor effect of cisplatin in drug-resistant ovarian cancer via induction of apoptosis and inhibition of cell migration and invasion

• Главные авторы: Haixia Wang (Автор), Youjun Luo (Автор), Tiankui Qiao (Автор), Zhaoxia Wu (Автор), Zhonghua Huang (Автор)
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• Опубликовано: BMC, 2018-11-01T00:00:00Z.
• Предметы: article
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Abstract Luteolin, a polyphenolic flavone, has been demonstrated to exert anti-tumor activity in various cancer types. Cisplatin drug resistance is a major obstacle in the management of ovarian cancer. In the present study, we investigated the chemo-sensitizing effect of luteolin in both cisplatin-r...