Role of the 5-HT1A autoreceptor in the enhancement of fluvoxamine-induced increases in prefrontal dopamine release by adrenalectomy/castration in mice

• Main Authors: Shigeru Hasebe (Author), Naoki Hiramatsu (Author), Yukio Ago (Author), Kazuya Mori (Author), Yuji Watabe (Author), Hitoshi Hashimoto (Author), Kazuhiro Takuma (Author), Toshio Matsuda (Author)
• Format: Book
• Published: Elsevier, 2015-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We have found that fluvoxamine-induced increases in prefrontal dopamine release are enhanced by adrenalectomy/castration and 5-HT1A receptors are involved in the enhancement. This study examined which 5-HT1A autoreceptors or postsynaptic receptor play a key role in the enhancement in mice. Adrenalec...