Protective Effect of Gemfibrozil on Hepatotoxicity Induced by Acetaminophen in Mice: the Importance of Oxidative Stress Suppression

• Main Authors: Hojatolla Nikravesh (Author), Mohammad Javad Khodayar (Author), Masoud Mahdavinia (Author), Esrafil Mansouri (Author), Leila Zeidooni (Author), Fereshteh Dehbashi (Author)
• Format: Book
• Published: Tabriz University of Medical Sciences, 2018-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Purpose: Gemfibrozil (GEM) apart from agonist activity at peroxisome proliferator-activated receptor-alpha (PPAR-α) has antioxidant and anti-inflammatory properties. Accordingly, the present study was designed to investigate the protective effect of GEM on acute liver toxicity induced by acetaminoph...