MMP14high macrophages orchestrate progressive pulmonary fibrosis in SR-Ag-induced hypersensitivity pneumonitis

• Main Authors: Dan Peng (Author), Juan Li (Author), Yin Li (Author), Lingling Bai (Author), Anying Xiong (Author), Xiang He (Author), Xiaolan Li (Author), Qin Ran (Author), Lei Zhang (Author), Manling Jiang (Author), Junyi Wang (Author), Elaine Lai-Han Leung (Author), Pingchang Yang (Author), Guoping Li (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fibrotic hypersensitivity pneumonitis (FHP) is a fatal interstitial pulmonary disease with limited treatment options. Lung macrophages are a heterogeneous cell population that exhibit distinct subsets with divergent functions, playing pivotal roles in the progression of pulmonary fibrosis. However,...