Analysis of Dengue Virus Genetic Diversity during Human and Mosquito Infection Reveals Genetic Constraints.

• Main Authors: October M Sessions (Author), Andreas Wilm (Author), Uma Sangumathi Kamaraj (Author), Milly M Choy (Author), Angelia Chow (Author), Yuwen Chong (Author), Xin Mei Ong (Author), Niranjan Nagarajan (Author), Alex R Cook (Author), Eng Eong Ooi (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Dengue viruses (DENV) cause debilitating and potentially life-threatening acute disease throughout the tropical world. While drug development efforts are underway, there are concerns that resistant strains will emerge rapidly. Indeed, antiviral drugs that target even conserved regions in other RNA v...