Epidermal growth factor receptor pathway as therapeutic development in head and neck cancers: present and future

• मुख्य लेखकों: Chancellor E. Donald (लेखक), Luis E. Raez (लेखक), Edgardo S. Santos (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2011-12-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

The understanding of the epidermal growth factor pathway in terms of intracellular signaling and its role in proliferation and cell survival has impacted the therapeutic management of many solid tumor malignancies in which this pathway has been dysregulated. Once the receptor is targeted at its cell...