Design of potent fluoro-substituted chalcones as antimicrobial agents

• Main Authors: Serdar Burmaoglu (Author), Oztekin Algul (Author), Arzu Gobek (Author), Derya Aktas Anil (Author), Mahmut Ulger (Author), Busra Gul Erturk (Author), Engin Kaplan (Author), Aylin Dogen (Author), Gönül Aslan (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Owing to ever-increasing bacterial and fungal drug resistance, we attempted to develop novel antitubercular and antimicrobial agents. For this purpose, we developed some new fluorine-substituted chalcone analogs (3, 4, 9-15, and 20-23) using a structure-activity relationship approach. Target compoun...