Clinical Characteristics and Whole Exome Sequencing Analysis in Serbian Cases of Clubfoot Deformity-Single Center Study

• Main Authors: Filip Milanovic (Author), Sinisa Ducic (Author), Milena Jankovic (Author), Sanja Sindjic-Antunovic (Author), Emilija Dubljanin-Raspopović (Author), Milica Aleksic (Author), Goran Djuricic (Author), Dejan Nikolic (Author)
• Format: Book
• Published: MDPI AG, 2024-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Recognized as one of the most serious musculoskeletal deformities, occurring in 1-2 per 1000 newborns, 80% of clubfeet are idiopathic while 20% present with associated malformations. The etiopathogenesis of clubfoot is described as multifactorial, including both genetic and environmental...