AQP3-mediated activation of the AMPK/SIRT1 signaling pathway curtails gallstone formation in mice by inhibiting inflammatory injury of gallbladder mucosal epithelial cells

• Główni autorzy: Ganggang Wang (Autor), Hao Zhang (Autor), Zhijie Zhou (Autor), Wenzhi Jin (Autor), Xin Zhang (Autor), Zenghui Ma (Autor), Xiaoliang Wang (Autor)
• Format: Książka
• Wydane: BMC, 2023-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Abstract Background Inflammatory injury of gallbladder mucosal epithelial cells affects the development of cholelithiasis, and aquaporin 3 (AQP3) is an important regulator of inflammatory response. This study reports a mechanistic insight into AQP3 regulating gallstone formation in cholelithiasis ba...