AQP3-mediated activation of the AMPK/SIRT1 signaling pathway curtails gallstone formation in mice by inhibiting inflammatory injury of gallbladder mucosal epithelial cells

• Päätekijät: Ganggang Wang (Tekijä), Hao Zhang (Tekijä), Zhijie Zhou (Tekijä), Wenzhi Jin (Tekijä), Xin Zhang (Tekijä), Zenghui Ma (Tekijä), Xiaoliang Wang (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: BMC, 2023-08-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

Abstract Background Inflammatory injury of gallbladder mucosal epithelial cells affects the development of cholelithiasis, and aquaporin 3 (AQP3) is an important regulator of inflammatory response. This study reports a mechanistic insight into AQP3 regulating gallstone formation in cholelithiasis ba...