Suppressing of Src-Hic-5-JNK-AKT Signaling Reduced GAPDH Expression for Preventing the Progression of HuCCT1 Cholangiocarcinoma

• Main Authors: Wen-Sheng Wu (Author), Rui-Fang Chen (Author), Chuan-Chu Cheng (Author), Jia-Ling Wei (Author), Chen-Fang Lin (Author), Ren-In You (Author), Yen-Chang Chen (Author), Ming-Che Lee (Author), Yen-Cheng Chen (Author)
• Format: Book
• Published: MDPI AG, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cholangiocarcinoma (CCA) is a malignant neoplasm of the bile ducts, being the second most common type of cancer in the liver, and most patients are diagnosed at a late stage with poor prognosis. Targeted therapy aiming at receptors tyrosine kinases (RTKs) such as c-Met or EGFR have been developed bu...